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List of labelling kits for the preparation of a technetium-99m labelled bone scanning agent

1. Labelling kits containing methylenediphosphonic acid (MDP, medronic acid)

Trade name Firm MDP Reducing Agent Others Max. Activity Shelf life (a)
SOLCO®SMDP SOLMED/SORIN BIOMEDICAL 25,0 mg SnF2: 0,2 mg Acidum aethylene-diamine-N, N, N\\\\\', N\\\\\'-tetrakis-methylene-phosphonicum: 0,8 mg 550 MBq 6 hours
Technetium Tc 99m Medronate Bracco Diagnostics Inc. 20,0 mg SnF2: 0,13-0,38 mg Ascorbic Acid: 1,0 mg
NaOH: 11,0 mg
740 MBq  
Technetium Tc99m Medronate For Injection Mallinckrodt Inc. 10,0 mg SnCl2.H2O: 0,8 mg p-aminobenzoic acid: 2,0 mg 740 MBq in 2-10 ml 6 hours
DRAXIMAGE MDP DRAXIMAGE 10,0 mg SnF2: 1,1 mg p-aminobenzoic acid: 2,0 mg 740 MBq 12 hours
Technetium[99mTc] Medronate Injection for Bone Scanning AUST R 14330 Radpharm Scientific Pty.Ltd. 10,0 mg SnCl2.H2O: 1,0 mg Ascorbic Acid: 1,0 mg  16000 MBq  8 hours
Technetium-99m Medronate Radiodiagnostic Reagent
MDP-10, MDP-21
Edmonton Radiopharmaceutical Centre 10,0 mg SnCl2.H2O: 0,92 mg Ascorbic Acid: 0,125 mg 555 MBq 12 hours
MEDROCIS%u2122 Schering Health Care Ltd 10,0 mg SnCl2.H2O: 1,0 mg Ascorbic Acid: 1,8 mg 11,1 GBq 8 hours
8-MDP Kit NO. 88/105/93-C Lacomed 8,0 mg SnCl2.H2O: 0,6 mg     8 hours
6-MDP Kit 88/105/93-C Lacomed 6,0 mg SnCl2.H2O: 0,45 mg Gentisic Acid: 1,0 mg    
Amerscan Medronate II Technetium Agent Amersham International plc 5,0 mg SnF2: 0,34 mg p-aminobenzoic acid: 2,0 mg 18-5 GBq 8 hours
MDP Tc-IK-10  Izotop, Institute of Isotopes Co. Ltd. 5,0 mg SnCl2.H2O: 0,6 mg Ascorbic Acid: 0,5 mg
Carbamide: 10,0 mg
6000 MBq  3 hours
99mTc-MDP
MTcK-8 - MTcK-8/3
POLATOM 5,0 mg SnCl2.H2O: 0,42 mg Ascorbic Acid: 2,0 mg
NaOH: 2,26 mg
   
LENOSCINT NORDION EUROPE S.A. 1,8 mg SnCl2.H2O: 0,45 mg Ascorbic Acid: 1,76 mg
NaOH: 0,09-0,12 mg
Sodium Chloride: 2,0 mg
700 MBq 8 hours
[99mTc]-MDP ROTOP® Pharmaka GmbH 5,0 mg SnCl2.H2O: 0,48 mg Ascorbic Acid: 0,5 mg 11,1 GBq 1 hour
IFE MDP TC.52S  ISOpharma 10,0 mg SnCl2.H2O: 0,3 mg Gentisic Acid: 1,0 mg   4 hours

(a) shelf-life : the time during which the preparation may be used after labelling with technetium-99m

  

2. Labelling kits containing hydroxymethylenediphosphonic acid (HDP, oxidronic acid)

Trade name Firm HDP Reducing Agent Others Max. activity Shelf life (a)
OSTEOCIS Schering Health Care Limited 3,0 mg SnCl2.H2O: 0,45 mg Ascorbic Acid: 0,75 mg  11100 MBq 6 hours
OSTEOCIS® PA 677/7/1 ElectraMed 3,0 mg SnCl2.H2O: 0,45 mg Ascorbic Acid: 0,75 mg  11100 MBq 8 hours
TCK-21 (b) Schering Health Care Limited 2,0 mg SnCl2.H2O: 0,30 mg Ascorbic Acid: 0,5 mg   6 hours
TechneScan® HDP Mallinckrodt Inc. 0,258 mg SnCl2.H2O: 0,297-0,343 mg Gentisic Acid: 0,84 mg  11100 MBq 8 hours

(a)   shelf-life : the time during which the preparation may be used after labelling with technetium-99m

(b) no longer available

   

3. Labelling kit containing 3,3-diphosphono-1,2-propanedicarboxylic acid, tetrasodium salt (DPD)

Trade name Firm DPD Reducing Agent Others Max. activity Shelf life
TECEOS%u2122 Schering Health Care Limited 13,0 mg 0,23 mg Gentisic Acid: 1,0 mg  11100 MBq 8 hours
       
4. Labelling kit containing 1-hydroxyethylidene-1,1-diphosphonic acid  (HEDP, EHDP)
Trade name Firm HEDP Reducing Agent Others Max. activity Shelf life
Phosphon in vivo kit (Tc-IK-1) Izotop, Institute of Isotopes Co. Ltd. 25,0 mg SnCl2.H2O: 1,0 mg NaCl 10,0 mg 3700 MBq  3 hours