NFCIS covers civilian nuclear fuel cycle facilities around the world. It contains information on operational and non-operational, planned, and cancelled facilities. All stages of nuclear fuel cycle activities are covered, starting from uranium ore production to spent fuel storage facilities.

Nuclear Fuel Cycle can be defined as the set of processes to make use of nuclear materials and to return it to normal state. It starts with the mining of unused nuclear materials from the nature and ends with the safe disposal of used nuclear material in the nature.