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flamprop-methyl |
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| Editor | I.G. Ferris |
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| Entity code | FLAMP | |
| CAS registry No. | 52756-25-9 | |
| Family | Arylalanine | |
| Functions | Herbicide | |
| Chemical name | methyl N-benzoyl-N-(3-chloro-4-fluorophenyl)-DL-alaninate (IUPAC, CAS) (EN) | |
| Synonyms | methyl (±)-N-benzoyl-N-(3-chloro-4-fluorophenyl)-2-aminopropionate | |
| Trade names | Metaven (Shell); Lancer (ICI) | |
| Other names | ||
| Last updated | 22/10/2008 | |
Fate
Toxicology
In mammals, following oral administration, metabolism and elimination occur within 4 days.
Mammals: Acute oral LD50 for rats 1210, mice 720 mg/kg. Acute percutaneous LD50 for rats >294 mg a.i./kg (as EC formulation). Non-irritating and non-sensitizing to skin. Acute i.p. LD50 for rats 350-500 mg/kg. In 2-year feeding trials, rats receiving 2.5 mg/kg diet and dogs receiving 10 mg/kg diet showed no ill-effects.
Detection
Sampling
Methods
MRLs
Uses
Post-emergence control of wild oats (Avena spp.) in wheat (including crops undersown with clover or grass), sugar beet, and fodder beet. Also control Alopecurus myosuroides.
Notes
Flamprop-methyl is a derivative of flamprop [58667-63-3].
The name “flamprop-méthyle” is used in France.
The D-isomer of this substance has the ISO common name flamprop-M-methyl.
Bibliography
US National Library of Medicine Flamprop-methyl (http://chem.sis.nlm.nih.gov/chemidplus/ProxyServlet?objectHandle=Search&actionHandle=getAll3DMViewFiles&nextPage=jsp%2Fcommon%2FChemFull.jsp%3FcalledFrom%3Dlite&chemid=052756259&formatType=_3D)
Pestizide Flamprop-methyl III–12.3 (http://www.toxcenter.de/stoff-infos/f/flamprop-methyl.pdf)
Mode of action
Selective systemic herbicide, absorbed by the leaves. Undergoes hydrolysis to flamprop, which is translocated readily in the phloem of the leaves basipetally to the stem. Inhibits cell elongation and cell division in the stem, and hence inhibits plant growth.
Ecotoxicology
Birds: Acute oral LD50 for bobwhite quail 4640 mg/kg; pheasants, mallard ducks, domestic fowl, partridges, pigeons >1000 mg/kg.
Fish: LC50 (96 hours) for rainbow trout 4.7 mg/l.
Bees: Not toxic to bees.
Plant metabolism & residues
In plants, flamprop-methyl is hydrolyzed to the biologically-active flamprop, which then undergoes conversion to a biologically-inactive conjugate.
| Property | Value | |
|---|---|---|
| Molecular weight | 0 | |
| Melting point | 0 °C | |
| Vapour pressure | 0 mPa | |
| Water solubility | 0 mg/l | |
| Octanol/water partition coefficient (log10 Kow) | 0 | |
| Dissociation constant | 0 |
Notes
| Property | Value | |
|---|---|---|
| Rat LD50 (oral) | 0 mg/kg bw | |
| Acceptable daily intake | 0 mg/kg/day |
Notes
| Property | Value | |
|---|---|---|
| Soil organic carbon partition coefficient (log10 Koc) | 0 l/kg | |
| Soil DT50 aerobic | 0 day |
Notes
| Property | Value |
|---|
Notes