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kadethrin
Editor	I.G. Ferris
Entity code	KADET
CAS registry No.	58769-20-3
Family	Pyrethroids
Functions	Insecticide
Chemical name	5-benzyl-3-furylmethyl (E)-(1R,3S)-2.2-dimethyl-3-(2-oxothiolan-3-ylidenemethyl)- cyclopropanecarboxylate (IUPAC) (EN)
Synonyms
Trade names	Kadethrin (Roussel Uclaf); Spray-Tox (Roussel Uclaf); RU 15525(Roussel Uclaf)
Other names
Last updated	8/2/2010

Fate
Kadethrin is used indoors. Little is published on the environmental fate.

Toxicology
In rats, following oral administation, there is rapid metabolism (by opening of the thiolactone ring, cleavage of the ester, and ring hydroxylation), and rapid excretion. See K. Ohsawa and J. E. Casida (J. Agric. Food Chem. 1980,28, 250-255).
Mammals: Acute oral LD50 for male rats 1324, female rats 650, dogs >1000 mg/kg. Acute percutaneous LD50 for female rats >3200 mg/kg. Slight irritant to skin,eyes, and respiratory tract. In 90-day feeding trials, no-effect level for rats was 25 mg/kg/day, and for dogs 15 mg/kg/day. No teratogenic effects observed in rats, mice, and rabbits.

Detection

Sampling

Methods

MRLs

Uses
Control of household insect pests, particularly houseflies, mosquitoes, and cockroaches. Normally used in combination with other pyrethroid insecticides and synergists.

Notes

Bibliography

Mode of action
Insecticide with contact action. Gives rapid knockdown.

Ecotoxicology
Fish: Toxic to fish.
Bees: Toxic to bees.

Plant metabolism & residues

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