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polyoxins |
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| Editor | I.G. Ferris |
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| Entity code | POLYO | |
| CAS registry No. | 19396-06-6 | |
| Family | ||
| Functions | ||
| Chemical name | 5-(2-amino-5-O-carbamoyl-2-deoxy-L-xylonamido)-5-deoxy-1-(1,2,3,4-tetrahydro-5 -hydroxymethyl-2,4-dioxopyrimidinyl)-?-D-allofuranuronic acid (polyoxin B) (IUPAC) (EN); 5-(2-amino-5-O-carbamoyl-2-deoxy-L-xylonamido)-5-deoxy-1-(1,2,3,4-tetrahydro-5 -carboxy-2,4-dioxopyrimidinyl)-?-D-allofuranuronic acid (polyoxin D) (IUPAC) (EN) | |
| Synonyms | ||
| Trade names | Polyoxin AL (polyoxin B); Piomycin (polyoxin B); Polyoxin Z (polyoxin D zinc salt); Piomy; Pio | |
| Other names | ||
| Last updated | 20/5/2003 | |
Fate
Toxicology
Mammals: Acute oral LD50 for male rats 21,000, female rats 21,200, male mice 27,300, female mice 22,500 mg/kg (polyoxin B); for male and female rats and mice >15,000 mg/kg (polyoxin D). Acute percutaneous LD50 for rats >20,000 mg/kg (polyoxin B). Non-irritant to mucous membranes and skin (rats). In 2-year feeding trials, no-effect level for rats and mice was >48,000 mg/kg diet (polyoxin B); for rats >50,000 mg/kg diet, and for mice >40,000 mg/kg diet (polyoxin D). Fish: LC50 (48 hours) for carp >40 mg/l (polyoxins B and D).
Detection
Sampling
Methods
MRLs
Uses
Mode of action: Systemic fungicide with protective action. Acts by inhibition of cell wall chitin synthesis.
Uses: Polyoxin B: Control of Alternaria spp. and powdery mildews in apples and pears; Botrytis cinerea in vines and aubergines; powdery mildews in roses, chrysanthemums, capsicums, and melons; blight of carnations; powdery mildew, brown spot, and grey mould in tobacco; powdery mildew and grey mould in strawberries; leaf mould, early blight and grey mould in tomatoes; powdery mildew, grey mould, gummosis, Sclerotinia rot, and Corynespora melonis in cucumbers; Alternaria blight in carrots; purple blotch in leeks; etc. Polyoxin D zinc salt: Control of sheath blight (Rhizoctonia solani) in rice; canker in apples and pears; Rhizoctonia solani, Drechslera, Bipolaris, Curvularia, and Helminthosporium spp. in lawn turf; etc.
Notes
Bibliography
Mode of action
Ecotoxicology
Plant metabolism & residues
| Property | Value | |
|---|---|---|
| Molecular weight | 0 | |
| Melting point | 0 °C | |
| Vapour pressure | 0 mPa | |
| Water solubility | 0 mg/l | |
| Octanol/water partition coefficient (log10 Kow) | 0 | |
| Dissociation constant | 0 |
Notes
| Property | Value | |
|---|---|---|
| Rat LD50 (oral) | 0 mg/kg bw | |
| Acceptable daily intake | 0 mg/kg/day |
Notes
| Property | Value | |
|---|---|---|
| Soil organic carbon partition coefficient (log10 Koc) | 0 l/kg | |
| Soil DT50 aerobic | 0 day |
Notes
| Property | Value |
|---|
Notes